急性冠状动脉综合征患者血浆B型钠尿肽及超敏C反应蛋白水平的临床分析

摘要

Objective To explore the clinical significance and the change of the plasm a levels of B-type natriuretic peptide (BNP) and hypersensitive C-reactive protein (hs-CRP)in patients with acute coronary syndromes.Methods The levels of BNP and hypersensitive CRP of 32 patients with unstable angina pectoris (UAP group) 28 patients with acute myocardial infarction (AM Ⅰ group )and 30 healthy controls(control group)were tested.Results The level of BNP of the patients with acute myocardial infarction was higher than the patients with unstable angina pectoris( P＜0.01 ) .The level of hs-CRP of the patients with acute myocardial infarction was higher than the patients with unstable angina pectoris( P＜0.05 ) .The levels of BNP and hs-CRP of the patients with unstable angina pectoris were higher than the healthy controls( P＜0.01 ) .Conclusion The levels of BNP and hs-CRP are important reference to the diagnosis and the risk stratification of ACS patients.%目的 探讨急性冠状动脉综合征患者血浆B型钠尿肽(BNP)和超敏CRP(hs-CRP)水平变化及临床意义.方法 对32例不稳定型心绞痛(UAP组)、28例急性心肌梗死患者(AMI组)和30例健康人(对照组)进行血浆BNP和超敏CRP水平检测.结果 急性心肌梗死患者血浆BNP水平高于不稳定心绞痛组(P＜0.01).急性心肌梗死患者血浆hs-CRP水平高于不稳定心绞痛组(P＜0.05).不稳定心绞痛组患者血浆BNP及hs-CRP水平高于对照组(P＜0.01).结论 血浆BNP及hs-CRP水平可以作为急性冠状动脉综合征患者诊断及危险分层的重要参考.