择期脑肿瘤切除术患者手术部位感染危险因素

摘要

Objective To explore the risk factors of surgical site infection(SSI)in patients undergoing selective brain tumor resection,and provide reference for clinical prevention and treatment.Methods Patients who under-went selective brain tumor resection in the neurosurgery department of a hospital during April-September 2013 and April-September 2014 were monitored prospectively,monitoring programme and individualized questionnaire were formulated,the basic data,operation condition,postoperative symptoms/signs,laboratory test results,infection-related factors,and antimicrobial use in patients were collected,risk factors for infection were analyzed.Results A total of 205 patients were investigated,23 (11 .22%)of whom had SSI;univariate analysis showed that body mass index (BMI),NNIS score,and cerebrospinal fluid leakage were related to the occurrence of SSI(all P<0.05);lo-gistic regression analysis showed that high NNIS score and cerebrospinal fluid leakage were independent risk factors for SSI in patients undergoing selective brain tumor resection(both P<0.05).Conclusion Incidence of SSI is high-er in patients with selective brain tumor resection,corresponding preventive measures should be taken according to different risk factors including cerebrospinal fluid leakage.%目的 探讨择期脑肿瘤切除患者手术部位感染的危险因素,为临床防治提供依据.方法 前瞻性监测2013年4—9月及2014年4—9月某院神经外科进行择期脑肿瘤切除术的患者,制定监测方案及个案调查表,收集其基本资料、手术情况、术后感染症状/体征及实验室检查结果、感染有关因素、抗菌药物使用情况等,并分析其感染危险因素.结果 共调查205例患者,其中23例发生手术部位感染,发病率为11.22%;单因素分析结果显示,身体质量指数(BMI)、NNIS评分、脑脊液漏与手术部位感染的发生有关(均P<0.05);logistic回归分析显示,NNIS评分高、脑脊液漏是择期脑肿瘤切除术患者手术部位感染发生的独立危险因素(均P<0.05).结论 择期脑肿瘤切除术患者手术部位感染发病率较高,在临床工作中,应针对包括脑脊液漏在内的不同危险因素采取相应的预防措施.