老年晚期非小细胞肺癌的预后因素分析

摘要

Objective To characterize the clinical features and prognostic analysis of advanced non-small cell lung cancer in elderly patients. Methods Review of 165 cases of lung cancer in elderly patients admitted to hospital in January 2007-January 2011, after cytological or pathological diagnosis. The clinical features, long-term survival were retrospectively evaluated. Results The median age was 70 years old, range from 65 to 89.The influence factors of 1-year survival rates of advanced non-small cell lung cancer in elderly patients were the sex (P=0.042), ECOG (P=0.016). The sex, ECOG and histological type were correlated with OS by univariate analysis(P<0.05). Furthermore, sex, ECOG were demonstrated to be prognostic factors by multivariate Cox regression analysis (P<0.05). Conclusion Advanced non-small cell lung cancer in elderly patients has unique characteristics, for which the treatment must be further studied.%目的：分析老年晚期非小细胞肺癌（NSCLC）的临床资料，探讨老年晚期NSCLC的预后分析。方法回顾分析2007年1月～2011年1月收治的经细胞学或痛理学确诊的165例老年肺癌患者，研究其临床特点、生存分析。结果165例老年肺癌患者，年龄65～89岁，平均70岁；老年NSCLC患者1年生存率的影响因素有性别（P=0.042）、ECOG评分（P=0.016）。单因素分析显示老年NSCLC患者的预后因素有性别、ECOG评分、组织学类型（P均＜0.05）；多因素分析显示老年NSCLC患者的预后因素有性别、ECOG评分（P均＜0.05）。结论老年晚期NSCLC具有独特的特点，其治疗方法需进一步探讨研究。