Objective To investigate the prevalence of depression and its risk factors in community elderly people at high risk of ischemic stroke .Methods Four hundred and sixty-nine elderly peo-ple with their age ≥60 years sampled from 4 communities in Hexi District of Tianjin were divided into depression group (n= 146) and non-depression group (n= 323) .Their depression was as-sessed according to the Hamilton's Depression Scale (edition 17) .Results Of the 469 elderly peo-ple at high risk of ischemic stroke ,146 (31 .1% ) suffered from depression .The incidence of de-pression was significantly higher in females ,singles ,those with a history of depression and heart disease ,those who had insufficient physical exercises ,physical labourers ,and those with a family history of ischemic stroke of depression group than in those of non-depression group (P<0 .05) . Logistic regression analysis revealed that females ,singles ,history of heart disease and family his-tory of ischemic stroke were the independent risk factors for depression in community elderly peo-ple at high risk of ischemic stroke (OR=2 .542 ,95% CI:1 .373 -4 .707 ,P= 0 .003 ;OR=4 .272 , 95% C I:1 .706-10 .696 ,P=0 .002 ;OR=2 .734 ,95% C I:1 .728 -4 .325 ,P=0 .000;OR=1 .583 , 95% CI:1 .013-2 .474 ,P=0 .044) .Conclusion Mild depression is more commonly observed in community elderly people at high risk of ischemic stroke .It should be diagnosed and treated as early as possible .%目的：调查社区老年脑卒中高危人群中抑郁状态的发生情况，探讨抑郁的危险因素及对抑郁早期发生的影响机制。方法采用分层随机整群抽样的方法，对天津市河西区4个社区年龄≥45岁的居民进行脑卒中高危人群的横断面筛查，登记人口基本情况及脑卒中危险因素，最终选择年龄≥60岁者469例，分为抑郁组146例，非抑郁组323例。应用汉密尔顿抑郁量表（HAMD，17项版本）对其抑郁状态进行评估。结果469例社区脑卒中高危者中，合并抑郁状态者146例，发生率为31．1％。与非抑郁组比较，抑郁组女性、单身、既往有抑郁病史、心脏病、缺乏体育锻炼或体力劳动及有脑卒中家族史比例明显升高，差异有统计学意义（P＜0．05）。多因素logistic回归分析显示，女性（OR＝2．542，95％CI：1．373～4．707，P＝0．003）、单身（OR＝4．272，95％CI：1．706～10．696，P＝0．002）、心脏病史（OR＝2．734，95％CI：1．728～4．325，P＝0．000）和脑卒中家族史（OR＝1．583，95％CI：1．013～2．474，P＝0.044）是社区老年脑卒中高危人群抑郁发生的独立危险因素。结论社区脑卒中高危人群以轻度抑郁状态多见，应对脑卒中高危人群进行抑郁量表筛查，早期诊断和早期干预抑郁状态。
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