老年2型糖尿病患者糖化血红蛋白水平与牙周指数的相关性研究

摘要

Objective:To investigate the effect of glycemic control on the periodontal index in elderly patients with type 2 diabetes mellitus (≥60 years).Methods:256 elderly patients with type 2 diabetes were selected and divided into 2 groups according to the value of glycosylated hemoglobin:good blood glucose control (≤ 8％) and poor blood glucose control (＞ 8％).Pocket depth (PD),attachment loss (AL),gingival index (GI),sulcus bleeding index (SBI),plaque index (PLI),dental calculus detection rate and furcation involvement were observed.Results:The age distribution,brushing habits,educational level,cigarette consumption and BMI index were similar in all groups (P＞0.05).Compared with the poor blood glucose control group,the patients in good group had shorter duration and higher economic income (P=0.006,P=0.001).In addition,there was no significant difference in PD,PLI,and calculus detection rate between good and poor groups (P＞0.05),but SBI,GI,AL and root bifurcation were statistically significant (P=0.001,P=0.002,P=0.0017,P=0.029).Conclusion:The higher the concentration of glycosylated hemoglobin in elderly patients with type 2 diabetes,the more severe destruction of periodontal tissue.%目的:探讨老年2型糖尿病患者糖化血红蛋白控制水平对各项牙周指数的影响.方法:以256名老年2型糖尿病患者为研究对象,按照糖化血红蛋白控制目标分为2组,血糖控制水平良好组(≤8％)和血糖控制水平欠佳组(＞8％),分析糖化血红蛋白变化对患者一般状况和探诊深度(PD)、附着丧失(AL)、牙龈指数(GI)、龈沟出血指数(SBI)、菌斑指数(PLI)、牙石检出率、根分叉病损等牙周指数的影响.结果:两组患者的年龄、刷牙习惯、教育水平、吸烟状况和BMI指数的构成分布基本相同(P＞0.05),与血糖控制水平欠佳组相比,良好组患者的病程较短而经济收入较高(P=0.006,P=0.001).牙周指数PD、PLI、牙石检出率在两组的比较中未见明显差异(P＞0.05),而SBI、GI、AL和根分叉病损差异具有统计学意义(P=0.001,P=0.002,P=0.017,P=0.029).结论:老年2型糖尿病患者糖化血红蛋白浓度越高,牙周组织的破坏程度越严重.