Five hundred and twelve patients with psudohypertrophic muscular dystrophy underwent rapidly minimally invasive muscle biopsy with TZ semi-automatic biopsy needle under intravenous anesthesia. Three hundred and seventy nine samples were taken from quadriceps femoris muscle, while other 133 samples were taken from the deltoid muscle. The pathological diagnosis was obtained in all patients and there were no complications after biopsy. The results indicated that this method was simple, safe, effective, indolent, and minimally invasive. The obtained muscle samples can meet the request of histopathological and immunohistochemical examination and the method should be recommended for clinical applicatioa.%探讨半自动活检针无痛微创肌活检在假肥大型肌营养不良中的应用方法和临床意义.应用TZ半自动活检针对512例假肥大型肌营养不良患者在静脉麻醉下进行快速微创肌活检.取股四头肌379例,三角肌133例,全部获得病理学诊断,术后无并发症.该方法操作简单、安全、有效、无痛、微创,所得的肌肉标本能够满足普通病理及免疫组化检查的要求,并对假肥大型肌营养不良的详细分型起到重要帮助作用.
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