Impedance-pH monitoring is a new technology for the detection of gastroesophageal reflux disease (GERD). it can distinguish the acid, weak acid or non-acid reiluxate via the pH and impedance value measured. Impfidanee-pH monitoring could be used for the diagnosis of GERD, especially for weak acid reflux or non-acid reflux, refractory GERD and atypical GERD. This article reviewed the mechanism and clinical application of impedance-pH monitoring.%阻抗-pH监测是目前监测胃食管反流病(GERD)的新技术,可通过对胃反流物的pH值和阻抗值进行检测,从而了解反流物为酸反流、弱酸反流或非酸反流,并可区分反流物的性状.阻抗-pH监测可应用于GERD的诊断,尤其适用于对弱酸反流或非酸反流的诊断、对难治性GERD的诊断以及非典型症状GERD的诊断.本文主要就阻抗-pH监测的机制和临床应用作一论述.
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