目的：对本院148例患者围术期预防感染抗生素的使用情况进行调查分析。方法随机抽选本院于2010年7月至2013年7月收治的148例手术患者。调查分析患者的手术种类、围术期用药时间、抗生素使用种类及药物联合使用情况。结果148例手术患者中Ⅰ类切口手术患者89例（60.14%）；Ⅱ类切口手术患者59例（39.86%）。围术期应用抗生素时间为2天者6例（4.05%）；3天者31例（20.94%）；4天者36例（24.43%）；5天者32例（21.62%）；6天者24例（16.22%）；6天以上者19例（12.74%）。应用最多的抗生素为头孢Ⅰ～Ⅱ代（25.89%）、β内酰胺酶抑制剂（18.27%）和头孢Ⅲ代（17.26%）。单一给药患者102例，占68.92%；二联用药患者43例，占29.05%；三联用药患者3例，占2.03%。结论本院在使用抗生素预防感染的过程中仍有选药不当、用药时间过长、盲目联合用药等问题存在，应重视并改正。%ObjectiveInvestigated 148 cases of patients with perioperative use of antibiotics to prevent infection.MethodsRandomly selected from July 2010 to July 2013 admitted during the period of 148 surgical patients. Investigation of the patients with operation types, perioperative duration, types of antibiotic use and drug usage.ResultsIn 148 cases of surgical patients,Ⅰclass incision surgery patients 89 cases (60.14%);Ⅱclass 59 patients with incision surgery (39.86%). The perioperative use of antibiotics for two days, 6 cases (4.05%);three days of 31 cases (20.94%); four days of 36 cases (24.43%); ifve days of 32 cases (21.62%); six days of 24 cases (16.22%); 6 days more than 19 cases (12.74%). Most applications forⅠ~Ⅱifrst-generation cephalosporin antibiotics (25.89%), beta lactamase inhibitor (18.27%) andⅢifrst-generation cephalosporin (17.26%). Using a single dose of patients 102 cases, accounting for 68.92% of all cases; 43 patients with duplex drugs, accounting for 29.05% of all cases; 3 patients with triple drug use, accounting for 2.03% of the total cases.Conclusion In our hospital in the process of use antibiotics to prevent infection is selected improperly, medication time is too long, blind combination problem, should pay attention to and correct.
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