ObjectiveTo investigate the clinical value of blood culture in the diagnosis and treatment of infective endocarditis.MethodRetrospectively analysed the ultrasonography results, clinical manifestations, blood cultureand results and therapeutic outcomes of 72 patients with infective endocarditis in our hospital from February 2013 to April 2014.ResultIn 72 patients, 64 cases (88.89%) of fever, 27 cases (37.50%) of splenomegaly, 8 cases (11.11%) of embolization, 22 cases (30.56%) of cardiac functionⅢ~Ⅳ, 4 cases (5.56%) of death. Ultrasound examination results of 41 patients with underlying heart disease showed that 18 cases of congenital heart disease, 14 cases of rheumatic heart disease, 9 cases of degenerative valvular disease. 33 patients underwent echocardiography, neoplasm position was respectively: 9 cases (27.27% ) in bicuspid valve, 8 cases in aortic valve (24.24%), 5 cases (15.15%) in bicuspid valve combined with aortic valve, 7 cases (21.21%) in pulmonary valve, 4 cases (12.12%) in tricuspid valve. Blood culture showed that 39 cases (54.17%) were positive and 33 cases (45.83%) were negative, streptococcus infection in 18 cases (25.00%), staphylococcia in 14 cases (19.44%), enterococcus faecalis infection in 5 cases (6.94%), fungal infection in 2 cases (2.78%).ConclusionEchocardiography has good diagnostic effect on the lesion site, blood culture can accurately determine the type of bacterial infection and drug sensitivity, it has a positive effect to guide the rational use of antibiotic treatment.%目的：探讨血培养联合超声心动图在感染性心内膜炎诊断及治疗中的临床应用价值。方法回顾性分析本院2013年2月至2014年4月收治的72例感染性心内膜炎患者的超声检查结果、临床表现、血培养及治疗结果。结果72例患者中出现发热64例（88.89%）、脾大27例（37.50%）、栓塞8例（11.11%）、心功能Ⅲ～Ⅵ级22例（30.56%）、死亡4例（5.56%）。41例伴基础性心脏病患者的超声检查结果：先天性心脏病18例、风湿性心脏病14例、退行性心瓣膜病9例。33例患者行超声心动图检查显示赘生物部位：二尖瓣9例（27.27%）、主动脉瓣8例（24.24%）、主动脉瓣合并二尖瓣5例（15.15%）、肺动脉瓣7例（21.21%）、三尖瓣4例（12.12%）。血培养阳性患者39例（54.17%）、阴性患者33例（45.83%），其中链球菌感染18例（25.00%）、葡萄球菌感染14例（19.44%）、粪肠球菌感染5例（6.94%）、真菌感染2例（2.78%）。结论超声心动图对病变部位具有较好的诊断效果，血培养能够准确判断患者细菌感染类型及药物敏感性，对于指导合理使用抗菌药物具有积极作用。
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