AMI患者彩色多普勒超声心动图结果与CK-MB、cTnI及CADi的关系

摘要

目的 探讨急性心肌梗死(acute myocardial infarction,AMI)患者彩色多普勒超声心动图结果与肌酸激酶同工酶MB(creatine kinase isoenzyme-MB,CK-MB)、心肌肌钙蛋白I(cardiac troponin I,cTnI)水平及冠心病指数(coronary artery disease index,CADi)评分的关系.方法 选择2014年8月至2016年8月本院确诊为AMI的120例患者为研究对象,采用酶联免疫吸附测定检测患者血清中CK-MB、cTnI水平,所有患者均行冠状动脉造影评价CADi评分及心脏彩色多普勒超声心动图,采用Pearson相关系数分析彩色多普勒超声心动图结果与CK-MB、cTnI水平及CADi评分的关系.结果 彩色多普勒超声心动图阳性患者CK-MB、cTnI水平及CADi评分均明显高于阴性患者(P<0.05),低射血分数(ejection fraction,EF)患者CK-MB、cTnI水平及CADi评分均明显高于高EF患者(P<0.05),左室舒张末期内径(left ventricular end-diastolic diameter,LVEDD)、EF与CK-MB、cTnI水平及CADi评分均呈正相关(P<0.05),而EF与CK-MB、cTnI水平及CADi评分均呈负相关(P<0.05).结论 CK-MB、cTnI水平及CADi评分有助于评价AMI患者病情严重程度及预后.%Objective To investigate the relationship between color Doppler echocardiography results and creatine kinase isoenzyme-MB (CK-MB), cardiac troponin I (cTnI) levels and coronary artery disease index (CADi) score in patients with acute myocardial infarction (AMI).Method 120 cases of patients with AMI were selected from August 2014 to August 2016 in our hospital as the research objects, levels of CK-MB and cTnI were detected by enzyme-linked immunosorbent assay, all patients were underwent coronary arteriongraphy to evaluate CADi score and Pearson correlation coefficient was used to discuss the relationship between color Doppler echocardiography and CK-MB, cTnI levels and CADi score.Result The levels of CK-MB, cTnI and CADi score in patients with color Doppler echocardiography positive were significantly higher than those of patients with color Doppler negative (P<0.05), the levels of CK-MB, cTnI and CADi score in patients with low ejection fraction (EF) were significantly higher than those of patients with high EF (P<0.05). The left ventricular end-diastolic diameter(LVEDD) and EF were positively correlated with the CK-MB, cTnI and CADi score (P<0.05), EF was negatively correlated with CK-MB, cTnI and CADi score (P<0.05).Conclusion CK-MB, cTnI levels and CADi score are helpful in evaluating the severity and prognosis of patients with AMI.