Composition comprising a monoclonal antibody or derivative thereof, which is immunologically reactive with CK-MB isoenzyme but not with CK-MM or CK-BB isoenzyme, cell line producing and method of producing such a monoclonal antibody, method of producing such a cell line, and method of determining CK-MB isoenzyme in a sample and of obtaining CK-MB from a mixture using the antibody

摘要

An improved method of determining CK-MB isoenzyme in a biological fluid is disclosed which comprises subjecting a sample of said fluid to an assay system which includes incubating with monoclonal antibody specific to CK-MIB isoenzyme, but not reactive with CK-MM or CK-BB. Methods for preparing antibodies with these characteristics and cell lines producing them are also disclosed.