骨髓间充质干细胞在眼科应用的研究进展

摘要

骨髓间充质干细胞(BMSCs)是骨髓组织中造血干细胞以外的一类成体干细胞,具有很强的自我更新能力、多向分化潜能及低免疫原性,可在特定的条件下诱导分化为不同的细胞,研究较为成熟的有成骨细胞、软骨细胞、脂肪细胞、心肌细胞、血管内皮细胞等,在组织工程学及细胞替代移植疗法中有广阔的应用前景.近年来,BMSCs因其自身的应用优势而成为眼科研究的热点.就BMSCs在眼科的应用研究进行综述.%Bone marrow mesenchymal stem cell (BMSC) is one kind of the adult stem cells.BMSCs have a strong capacity of self-renewal,the ability to differentiation into different cell types and low immunogenicity.The cells have been successfully differentiated into osteoblast,cartilage cells,adipose cells,cardiac muscle cells and vascular endothelial cells and have a bright future in the field of tissue engineering and cell transplantation.Resent years,BMSCs become the hot spot in ophthalmology due to their advantages.This paper summarizes the effects of BMSCs in the research of ophthalmology.