CINAHL是护理学权威数据库,为目前全球最大的护理及相关健康领域文献数据库,且覆盖了诸多学科领域.CINAH数据库的检索技术包括字段限定检索、布尔逻辑检索、截词检索、位置检索和短语检索.本文介绍了高级检索、基本检索、视觉搜索、主题词检索、出版物浏览、参考文献检索、索引检索及循证护理说明等检索方法与技巧.本文还探讨了检索结果页面的3个区域:精确检索结果区域、检索结果显示区域(检索结果显示、检索结果排序和检索结果保存)及相关资讯区域.%Objective To discuss the correlation between polymorphism of interleukin-6 (IL-6) gene-572C/G and risk of ischemic stroke (IS) in Chinese population.Methods The databases of PubMed, EMbase, CBM, CNKI and WanFang Database were retrieved with computer for searching the case-control studies on the correlation between polymorphism of IL-6 gene-572C/G and risk of IS in Chinese population up to Dec. 2015. The literature was screened and data was extracted by 2 researchers independently according to inclusion and exclusion criteria, and after quality review on methodology the data was given a Meta-analysis by using Stata 12.0 software. Results There were totally 8 case-control studies including 1870 cases of IS patients and 1915 health controls. The results of Meta-analysis showed that polymorphism of IL-6 gene-572C/G might increase the risk of IS in Chinese population (Gvs. C:OR=1.38, 95%CI: 1.14~1.67; GCvs. CC:OR=1.50, 95%CI: 1.26~1.78; GG+GCvs. CC:OR=1.53, 95%CI: 1.26~1.85). The results of analysis in subgroups grouped according to race showed that the risk of IS was more significant in Han population, and decreased in Uygur population.Conclusion The polymorphism of IL-6 gene-572C/G can increase the risk of IS in Chinese population, especially in Han population. As the quantitative limitation of included studies, the conclusion is needed further verification.
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