白蛋白结合型紫杉醇(Abraxane)联合替吉奥(S-1)一线治疗晚期胃癌的临床观察

摘要

This paper won the Three Prize for Prize Essay for Experience Sharing of Chinical Application of Albumin-bound PaclitoxelrnObjective: To observe the eftect and security of advanced gastric cancer treaded in line by Abraxane combined with S-l. Methods: The usage of Abraxane 125 mg/m2, D1 and D8, the usage of S-l 60mg/m2 Bid P. O. D1-14, after three weeks repeated, at least completed 2 cyclical chemotherapies. Results: The cases of PR, SD and PD in 19 patients were 11,4 and 4 with mild loxicity. Conclusion: Advanced gastric cancer treated in line by Abraxane combined with S-l will show vast foreground of treatment.%目的:观察白蛋白结合型紫杉醇(Abraxane)联合替吉奥(S-1)一线治疗晚期胃癌的疗效和安全性.方法:Abraxane125 mg/m2,在化疗的第1和第8天,S-1每天60 mg/m2,分2次,从化疗的第1到第14天;3周为一个周期,至少完成2个周期.结果:19例患者PR 11例,SD4例,PD4例,毒副反应可以耐受.结论:白蛋白结合型紫杉醇作为一种新型紫杉类化疗药联合替吉奥一线治疗晚期胃癌具有广阔研究前景.