目的 探讨老年高血压伴有血同型半胱氨酸增高(H型高血压)患者肾功能受损情况.方法 将60岁以上原发性高血压263例患者,按血同型半胱氨酸的检验值分为:非H型高血压组、H型高血压1组、H型高血压2组,测定3组病例的24h尿微量蛋白,将3组病例的24 h尿微量蛋白进行比较.结果 H型高血压2组患者血同型半胱氨酸(24.83±4.00)μmol/L虷型高血压1组患者血同型半胱氨酸(15.73±3.84) μnol/L较非H型高血压组(6.14±3.58) μmol/L显著增高(P＜0.01)；H型高血压2组患者24h尿微量蛋白(24.83±4.00)mg/L较H型高血压1组患者24h尿微量蛋白(15.73±3.84)mg/L亦显著增高(P＜0.01).结论 老年H型高血压患者更易发生肾脏损害.%Objective To compare urine microprotein in elderly hypertension patients with hyperhomocys-teine ( H-type hypertension). Methods 263 elderly hypetension patients were divided into three groups according to the levels of blood homocysteine,i. e. non-H-type hypertension patients,H-type hypertension elderly patient group 1 and 2. Levels of 24-houi urine microprotein in each group were detected and compared. Results The levels of 24-hour urine microprotein in either H-type hypertension group 2 (24.83 ±4.00) or group 1 (15.73 ±3.84) were significantly higher than that of non-H-type hypertension group (6.14 ±3. 58) (P＜0.01). Moreover, the level of 24-hour urine microprotein in H-type hypertension group 2 (24.83±4.00) was higher than (15.73 ±3. 84) H-type hypertension group 1 (P＜0.01). Conclusion Elderly patients with H-type hypertension have higher risk for the oc-curance of kidney iniury.
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