钯催化烯丙基磺酰胺的分子内胺氟化反应

摘要

报道了钯催化的非活性烯烃的胺氟化反应，在酸性添加剂HOAc的作用下，反应以较好的收率和区域选择性地得到6-endo环合产物，实现了氟代的环状磺胺类产物的有效合成。%A facile Pd‐catalyzed intramolecular aminofluorination reaction of allylic sulfamides was developed that can be used to prepare fluorinated 1,3‐diamine derivatives. Acetic acid was essential for regula‐tion to give the major 6‐endo cyclization products.