Objective To study the rationality of hypoglycemic drugs in patients with gastroparesis. Methods The mechanism of gastroparesis was analyzed, and the mechanism, indications, adverse reactions and contraindications of common hypoglycemic agents were studied. Results There were significant differences in the mechanism of gastric hypoglycemia and hypoglycemic therapy. The mechanism of action and the application of the patients were obvious. According to the characteristics of the patients, the selection of the appropriate drugs could improve the clinical curative effect and ensure the safety of the drug. Conclusion The pathogenesis of gastroparesis is more complicated. The clinical practice should be based on the pathogenesis of the patients and the hypoglycemic drug regimen.%目的 探讨胃轻瘫患者降糖药物的应用合理性.方法 分析胃轻瘫发病机制,并对常用降糖药物作用机制、适应证、不良反应及禁忌证等进行研究.结果 胃轻瘫降糖治疗药物类型较多,其作用机制及适用人群存在明显差异,根据患者病情特征、机体状况等选用适宜药物可改善临床疗效、保证用药安全性.结论 胃轻瘫发病机制较复杂,临床实际应根据患者发病原因、机体功能状态制定降糖药物治疗方案.
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