难治性癫痫的定义和治疗选择

摘要

国际抗癫痫联盟将难治性癫痫定义为经2种耐受性好的抗癫痫药物单药或联合使用后,患者没有达到无发作.难治性癫痫往往需要多种药物联合治疗,甚至寻求其他的治疗方案(生酮饮食、外科治疗等).因此,掌握难治性癫痫的概念,同时熟悉各种治疗的优缺点,对于减少患儿的发作、改善认知、提高患儿的生活质量有非常重要的意义.%International League Against Epilepsy define intractable epilepsy as failure of adequate trials of 2 used antiepileptic drugs schedules (whether as monotherapies or in combination) to achieve seizure freedom.Intractable epilepsy often requires a combination of drugs,or other treatment options (ketogenic diet,surgical treatment,etc.).Therefore,it is very important to familiar with the definition of intractable epilepsy,also the main characteristics of the treatments,which can reduce the onset of children,improve cognition,and improve the patient's quality of life.