蛋氨酸来源调控机体蛋氨酸代谢的研究进展

摘要

蛋氨酸是畜禽必需氨基酸之一,常用蛋氨酸类添加物包括DL-蛋氨酸(DL-methionine,DLM)和蛋氨酸羟基类似物(Methionine hydroxyl analogue,MHA)等.关于此两类蛋氨酸源生物学效价研究较多,但结果并不一致,因此近年来的研究试图揭示不同蛋氨酸源调控蛋氨酸代谢的规律,以寻求效价异同的理化机制.本文综述了近年来有关蛋氨酸源在动物体内吸收和代谢方面的研究,以便为正确评价其生物学效价和在生产实践中合理使用提供理论依据.%Methionine is the first-limiting amino acid in most poultry diets. Two sources, methionine hydroxyl analogue (MHA) and Met (DLM), are commercially available. Numerous studies have been conducted to compare the efficacy of MHA and DLM. However, the results of several of these studies have been inconclusive or seemed to be inconsistent. More and more researches have been done to compare the metabolism of MHA and DLM in their utilization as sources of L-Met. The research advances in the regulation of Met metabolism by Met sources and levels have been reviewed in this paper. The attempt to investigate the metabolic difference between MHA and DLM is helpful not only to explain the inconsistent results on bioefficacy of the two sources, but also for properly utilizing Met sources in diet formulation.