高强度聚焦超声在前列腺癌治疗中的应用

摘要

Some early researches suggest that high intensity focused ultrasound ( HIFU ) is effective on selected patients with prostate cancers. Two devices are currently used for the treatment of prostate cancer with HIFU: Sonablate ( USA ) and Ab-latherm ( France ) . The outcomes [ ie, biochemical free survival rate ( BFSR ), prostate special antigen ( PSA ) and negative postoperative prostate biopsies ] achieved for primary - care prostate cancer patients are very satisfactory. Moreover, HIFU is a potential treatment for local recurrence after radiation failure.%一些早期的研究报道显示,对于选择性的前列腺癌患者,高强度聚焦超声(HIFU)是一种有效的治疗方法.目前有两种设备用于前列腺癌的HIFU治疗,即美国生产的Sonablate设备和法国生产的Ablatherm设备.一些研究初步发现HIFU对前列腺癌患者的治疗结果(如生化无病生存率、前列腺特异性抗原、术后前列腺穿刺活检阴性)良好.另外,对于前列腺癌放射治疗后局部复发的患者,HIFU是潜在的治疗方式.本文就HIFU在前列腺癌治疗中的应用进展进行综述.