新疆维吾尔族和汉族多囊卵巢综合征临床特征分析

摘要

Objective To discuss the differences of clinical features and metabolism between Uygur and Han patients with polycystic ovary syndrome. Methods According to the Revised 2003 European Society for Human Reproduction and Embryology/American Society for Reproductive Medicine criteria PCOS can be diagnosed with 2 manifestations out of oligo - or anovulation , clinical and/or biochemical signs of hyperandrogenism exclusion of other etiologies and polycystic ovaries. Two hundred and ten PCOS patients ( Han patient 132, Uygur 78 ) admitted into the clinic of the First Affiliated Hospital of Xinjiang Medical University from August 2009 to May 2010 were included in this retrospective study. Results ( 1 ) There were no differences between two groups in age , body mass index and waist - hip ratio ( P ＞ 0. 05 ). Oligomenorrhea showed no difference hetween the two groups ( Han patient 52. 38％ , Uygur 46. 15 ％ ). The relevant sample size was less than normal. F - G scores of the two groups were significantly different ( Han patient 42/132, Uygur 59/78 ) and were specifically related to race. ( 2 ) LH/FSH ratios of Uygur ( Uygur 2. 79 ± 1. 97 , Han patient 2. 06 ± 1. 19 ) were significantly higher than that of Han patients ( P ＜0. 05 ). ( 3 ) The difference of total cholesterol between the two groups was statistically significant ( P ＜ 0. 05 ). Conclusion According to ESHRE/ASRM criteria, no significant differences are found in oligomenorrhea, Type - B ultrasonic manifestation of polycystic ovary and insulin metaholism between Uygur and Han childbearing age women with PCOS , hut significant differences are found in endocrine and blood lipid metabolism. Great importance should be attached to the metabolic disorders caused by PCOS and late stage complications should also be prevented positively.%目的 探讨维吾尔族(维族)和汉族多囊卵巢综合征(PCOS)患者的临床特征及相关物质代谢之间的差异.方法 回顾性分析我院2009年8月-2010年5月收治的210例PCOS患者的临床特征以及各项临床检查指标,其中汉族132例、维族78例.结果 (1)维汉两族患者的年龄、体质指数、腰臀比间差异无统计学意义(P＞0.05),两组患者均存在月经稀发情况(汉族52.38%、维族46.15%),但差异无统计学意义(P＞0.05).两组F-G分数(汉族42/132、维族59/78)间差异有统计学意义(P＜0.05).(2)维族和汉族的黄体生成素/卵泡雌激素[汉族(2.06±1.19)、维族(2.79±1.97)]间差异有统计学意义(P＜0.05).(3)维族和汉族总胆固醇水平间差异有统计学意义(P＜0.05).结论 按照ESHRE/ASRM诊断标准,维、汉两族育龄妇女PCOS患者的稀发排卵、卵巢多囊B超表现以及胰岛素代谢方面无明显差异,而女性内分泌及血脂代谢方面有差异,应重视PCOS疾病引起患者体内物质代谢紊乱的现象以及积极预防后期并发症.