Objective To explore the characteristics of glucose metabolism of women with polycystic ovary syndrome (PCOS)with or without obesity in Xinjiang Uyghur and Han nationalities.Methods An epide-miological survey was conducted on PCOS among Uyghur and Han population in Xinjiang,obese and non-obese PCOS patients were grouped according to the survey,and the differences of glucose metabolism and IR in obese and non-obese patients in Uyghur and Han nationalities were analyzed.Results (1)The rate of PCOS in Xinjiang was 5.11%.(2)In 722 PCOS patients 188 cases were obese,with 67.02% Han obesi-ty and 32.98% Uyghur (P <0.05);the rate of obese PCOS in Xinjiang was 26.04%.PCOS patents with obesity in Uyghur was fewer than Han.(3)The occurrence of abnormal glucose metabolism in Uyghur and obese patients was higher than that of Han and non-obesity patients.(4)The level of blood insulin and glucose at the time of 0,30,60,120 and 180 minutes in obese patients was higher than that of non-obesity group (P <0.05);Uyghur obese patients had higher level of blood insulin and glucose at the time of 0, 30,60 and 120 minutes than Han nationality (P <0.05).However,the level of blood insulin and glucose did not exhibit significant difference between obese and non-obese group (P > 0.05 )at time of 180 minutes.IR in obese group was higher than that in non-obese patients in both nationalities,and they were (3.4±1.1),(3.1±1.3)and (1.5±0.7),(1.4±0.6)respectively (P <0.05);However,obese Uyghur pa-tients had higher IR than Han (P <0.05).Conclusion The incidence of PCOS was 5.11%;there were more obese PCOS patients in Uyghur than in Han nationality in Xinjiang child-bearing women,and more abnormal glucose metabolism and IR in Uyghur obese PCOS patients,so more attention should be paid to the early abnormal glucose metabolism in Uyghur obese PCOS patients for the early clinical treatment.%目的：探讨新疆维吾尔族（维族）、汉族多囊卵巢综合征（PCOS）患病情况及肥胖与非肥胖患者胰岛素抵抗和糖代谢特征的异同。方法对新疆维、汉族不同地区人群中多囊卵巢综合征患病情况进行流行病学调查，对调查出的 PCOS 患者按照体质指数（BMI）分为肥胖组和非肥胖组，分析不同民族肥胖与非肥胖患者胰岛素抵抗和糖代谢的异同。结果（1）新疆 PCOS 发生率为5．11％；（2）调查出的722例 PCOS 患者中肥胖者188例，占26．04％，其中汉族肥胖者占67．02％，维吾尔族肥胖者占32．98％，维吾尔族 PCOS 患者发生肥胖者少于汉族。（3）维吾尔族和汉族不同体质指数 PCOS 患者的发生情况，差异有统计学意义（P ＜0．05），维吾尔族患者及肥胖患者发生糖代谢异常高于汉族及非肥胖患者。（4）维吾尔族、汉族肥胖组患者空腹及服糖后30、60、120、180 min 血糖及胰岛素水平均高于非肥胖组，差异均有统计学意义（P ＜0．05）；而维吾尔族肥胖组空腹及服糖后30、60、120 min 血糖及血胰岛素水平均高于汉族肥胖组，差异均有统计学意义（P ＞0．05）。但两组服糖后180 min 血糖及胰岛素水平比较差异无统计学意义（P ＞0．05）。维吾尔族和汉族肥胖胰岛素抵抗（IR）较非肥胖患者多见，IR 分别为（3．4±1．1）、（3．1±1．3）和（1．5±0．7）、（1．4±0．6）（P ＜0．05），且维吾尔族肥胖患者 IR 较汉族严重（P ＜0．05）。结论新疆地区维吾尔族肥胖 PCOS 患者较汉族多见，而肥胖 PCOS 患者糖代谢异常及 IR 更为明显，对维吾尔族肥胖患者更应重视早期的糖代谢异常。
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