Objective To investigate the correlation between left atrial appendage morphology and cardioembolic stroke. Methods 102 patients who had coronary artery CT angiography( CTA)and brain CT or MRI in Second Artillery General Hospital of PLA from December 2014 to August 2015 were enrolled. According to the general clinical diagnosis of specialist physicians,the patients were divided into cardioembolic stroke group of 66 cases and non-stroke group of 36 cases. CT three-dimensional reconstruction was applied to separate left atrial appendage image,and observed its morphology and morphology of its opening,and measured its volume and maximum diameter of its opening. Results There was significant difference in age, prevalence of diabetes,coronary heart disease prevalence and volume of left atrial appendage between two groups( P﹤0. 05 );while there was no significant difference in gender,prevalence of hypertension,and maximum diameter of left atrial appendage opening( P﹥0. 05 ) . The morphological distributions of left atrial appendage in two groups were significantly different( P ﹤0. 05 );while the morphological distributions of left atrial appendage openings in two groups were not significantly different( P﹥0. 05). Age,diabetes,coronary heart disease,volume of left atrial appendage,and morphology of left atrial appendage were positively correlated with the occurrence of cardioembolic stroke( values of rs were 0. 329,0. 291,0. 256,0. 242,and 0. 319 respectively,P﹤0. 05 ) . Conclusion Volume and morphology of left atrial appendage are correlated with the occurrence of cardioembolic stroke.%目的：探讨左心耳形态与心源性脑卒中的相关性。方法选取2014年12月—2015年8月在中国人民解放军第二炮兵总医院就诊的已行冠状动脉CT血管造影（ CTA）和颅脑CT或MRI的患者102例，根据专科医生临床诊断分为心源性脑卒中组66例和非脑卒中组36例。采用CT三维重建分离左心耳图像，观察左心耳形态、左心耳开口形态，并测量左心耳体积、左心耳开口最大直径。结果两组年龄、糖尿病患病率、冠心病患病率、左心耳体积间差异有统计学意义（P﹤0.05）；而性别、高血压患病率、左心耳开口最大直径间差异无统计学意义（P﹥0.05）。两组左心耳形态分布间差异有统计学意义（P﹤0.05）；而左心耳开口形态分布间差异无统计学意义（P﹥0.05）。年龄、糖尿病、冠心病、左心耳体积、左心耳形态与心源性脑卒中的发生均呈正相关（ rs 值分别为0.329、0.291、0.256、0.242、0.319，P﹤0.05）。结论左心耳的体积、形态与心源性脑卒中发生相关。
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