奥曲肽联合普萘洛尔治疗肝硬化上消化道出血的效果分析

摘要

Objective:To explore the clinical effects of Octreotide combined with Propranolol in the treatment of liver cirrhosis with upper gastrointestinal bleeding.Method:150 cases,received from September 2011 to September 2013,suffering from liver cirrhosis with upper gastrointestinal bleeding were divided into observation group and control group,75 cases in each group.The patients in the control group were treated with Octreotide based on conventional treatment, on the basis of this,the patients in the observation group were treated with Propranolol.The clinical efficacy,bleeding and hospitalization time in two groups were compared.Result:The average hemostasis time and the hospitalization time in the observation group were significantly shorter than those in the control group, the differences were significant(P<0.05).The clinical total effective rate in the observation group was 90.67%,which was significantly better than 76.00%in the control group,the difference was statistically significant (P<0.05).Conclusion:Octreotide combined with Propranolol in the treatment of liver cirrhosis with upper gastrointestinal bleeding is remarkable,worthy of promotion.%目的：探讨奥曲肽联合普萘洛尔治疗肝硬化合并上消化道出血的临床治疗效果。方法：选取2011年9月-2013年9月笔者所在医院收治的150例肝硬化导致的上消化道出血患者，随机分为对照组和观察组，每组75例，对照组在常规治疗基础上应用奥曲肽，观察组在对照组治疗基础上加用普萘洛尔，比较两组临床疗效、止血时间和住院时间。结果：观察组患者平均止血时间及平均住院时间均显著短于对照组，差异有统计学意义(P<0.05)。观察组临床总有效率为90.67%，显著优于对照组的76.00%，差异有统计学意义(P<0.05)。结论：奥曲肽联合普萘洛尔治疗肝硬化合并上消化道出血的临床治疗效果显著，值得推广。