妊娠期妇女甲状腺功能减退的患病率及危险因素调查

摘要

Objective:To investigate the prevalence and risk factors for hypothyroidism on pregnancy.Method:In this study,we observed 628 pregnant women in Maternal and Child Health Hospital of Zhengzhou City Command from Jan 2012 to Jan 2013.Tested their thyroid function to valuation of the thyroid function.Result:113 pregnant women were diagnosed to be Subclinical hypothyroidism,prevalence of subclinical hypothyroidism was 17.99%,4 pregnant women were overt hypothyroidism,prevalence of overt hypothyroidism was 0.64%.The TSH rising incidence progressively increased with BMI in the pregnant women (χ²=573.40,P<0.05),age had no effect on pregnanct women elevated TSH(χ²=0.437,P>0.05).Conclusion:Subclinical hypothyroidism during pregnancy has a high prevalence,BMI was risk factor.Screening in pregnancy should be strengthened.%目的：了解目前郑州市妊娠期妇女的甲状腺功能减退的患病率情况，分析其危险因素。方法：对2012年1月-2013年1月来笔者所在医院就诊的628名妊娠期妇女进行甲状腺功能指标检测，评价其甲状腺功能。结果：亚临床甲状腺功能减退的患者为113例，患病率为17.99%，临床甲状腺功能减退患者为4例，患病率为0.64%。随着体重指数的增加，孕妇TSH升高的发生率也增高(χ²=573.40，P<0.05)；年龄对妊娠期妇女TSH升高没有影响(χ²=0.437，P>0.05)。结论：妊娠期妇女亚临床甲状腺功能减退的患病率较高，体重指数是其危险因素，应加强防治，做好怀孕前及孕期的筛查。