C-反应蛋白在冠心病患者病情严重程度中的诊断价值

摘要

目的：探讨C-反应蛋白(CRP)在冠心病患者病情严重程度中的检测价值。方法：选取2011年10月-2012年8月笔者所在医院收治的100例冠心病患者为研究对象，按照病情严重程度的不同分为稳定型心绞痛(SAP)、不稳定型心绞痛(UAP)和心肌梗死(AMI)三组，测定三组患者的CRP水平，并根据CRP水平的不同分为高CRP组和低CRP组，比较两组的心血管不良事件和左室射血分数(LVEF)。结果：AMI组的CRP显著高于UAP组，UAP组的CRP显著高于SAP组(P<0.05)。高CRP组的心血管不良事件显著高于低CRP组，LVEF显著低于低CRP组(P<0.05)。结论：CRP与冠心病的发生有关，其可能介导了动脉粥样硬化的形成，对预测冠心病患者的病情具有重要的检测价值。%Objective:To investigate the diagnostic value of C-reactive protein(CRP) in disease severity in patients with coronary heart disease. Method:From October 2011 to August 2012 100 cases of coronary heart disease patients were selected as the research object,according to the illness severity they were divided into SAP group UAP group and AMI group,determination the levels of CRP of three groups,according to the levels of CRP they were divided into high CRP group and low CRP group,compared the cardiovascular adverse events and LVEF of two groups.Result:The CRP of AMI group was significantly higher than that of UAP group,CRP was significantly higher than in SAP group and UAP group(P<0.05).High CRP group of cardiovascular adverse events was significantly higher than that of low CRP group,LVEF was significantly lower than low CRP group(P<0.05).Conclusion:CRP and the occurrence of coronary heart disease, which may mediate the formation of atherosclerosis,coronary heart disease in predicting disease detection has important value.