替米沙坦联合比索洛尔治疗中青年舒张期高血压的疗效观察

摘要

Objective:To observe the efficacy and safety of telmisartan combined with bisoprolol treatment in young isolated diastolic hypertension. Method:Selected 32 cases isolated diastolic hypertension in early or poor treatment form January 2010 to January 2013,aged from 35 to 55 years,mean ages were (43.3±6.5)years,were given telmisartan tablets and bisoprolol treatment for 8 weeks,observing the changes of blood pressure,liver function,kidney function,blood sugar,blood fat and blood uric acid.Result:Diastolic blood pressure was (106.9±4.7)mm Hg before treatment,it was (88.0±5.3)mm Hg after treatment;Diastolic blood pressure dropped by(18.9±6.7)mm Hg,but systolic blood pressure dropped by only (10.9±3.7)mm Hg.Heart rate was (89.6±3.7) beats/min,yet it was (73.2±4.2)beats/min after treatment,which dropped by (16.6±5.7)beats/min compared with treatment.The difference was statistically significant(P<0.05),and the blood pressure,liver function,kidney function,blood sugar,blood fat and blood uric acid were no significant change. Conclusion:Telmisartan combined with bisoprolol treatment for young isolated diastolic hypertension is satisfactory results,and no significant adverse reactions.%目的：观察替米沙坦联合比索洛尔治疗中青年单纯舒张期高血压的疗效及安全性。方法：选择2010年1月-2013年1月初发或治疗效果不佳的32例单纯舒张期高血压患者，年龄35~55岁，平均(43.3±6.5)岁，予替米沙坦片比索洛尔片治疗8周，观察血压变化情况及肝肾功能、血糖、血脂、血尿酸变化。结果：治疗前舒张压(106.9±4.7)mm Hg，治疗后舒张压(88.0±5.3)mm Hg，舒张压下降了(18.9±6.7)mm Hg，而收缩压只下降了(10.9±3.7)mm Hg。治疗前心率(89.6±3.7)次/min，治疗后心率(73.2±4.2)次/min，较治疗前下降了(16.6±5.7)次/min，治疗前后比较差异有统计学意义(P<0.05)，而肝肾功能、血糖、血脂、血尿酸则无明显改变。结论：替米沙坦联合比索洛尔治疗中青年单纯舒张期高血压效果满意，无明显不良反应。