雾化吸入治疗婴幼儿哮喘急性发作临床疗效及C反应蛋白水平观察

摘要

目的：探讨雾化吸入治疗婴幼儿哮喘急性发作的临床疗效及C反应蛋白水平变化。方法：将120例婴幼儿哮喘急性发作患儿分为两组，对照组采用常规治疗，观察组联合雾化吸入治疗。结果：治疗4、7d后观察组夜间哮喘评分高于对照组。观察组喘憋缓解、咳嗽消失、肺部体征消失、平均住院时间明显低于对照组(P<0.05)。观察组治疗后外周血WBC计数及血清hs-CRP水平低于治疗前(P<0.01)，SaO2高于治疗前(P<0.01)。结论：雾化吸入治疗效果理想，可显著提高SaO2，血清hs-CRP定量检查可作为病情观察及指导治疗的一项指标。%Objective:To investigate the clinical efficacy of inhalation in the treatment of infants with acute asthma and the change of C-reactive protein(CRP) levels.Method:120 cases with acute exacerbation of asthmatic children were divided into two groups,the control group was taken conventional therapy,the observation group was combined with inhalation therapy.Result:The nocturnal asthma score after 4 days,7 days in the observation group was higher than that in the control group(P<0.05).Wheezing ease,cough disappeared,pulmonary symptoms disappear,the average hospital stay in the observation group were significantly lower than those in the control group(P<0.05).Peripheral WBC count and serum hs-CRP levels after treatment were lower than before treatment in the observation group(P<0.01),SaO2 was higher than before treatment(P<0.01).Conclusion:The therapeutic effect of inhalation is well,it can significantly improve the SaO2,quantitative examination of serum hs-CRP can be used as an indicator of the condition of observation and to guide treatment.