肌红蛋白联合肌钙蛋白检测在急性心肌梗死患者早期诊断中的临床意义

摘要

目的：探讨肌红蛋白联合肌钙蛋白检测在急性心肌梗死患者早期诊断中的临床意义。方法：选取笔者所在医院于2014年5月-2015年4月收治的急性心肌梗死患者85例作为研究组。另选同期在笔者所在医院行体检的健康受试者90例作为对照组。比较分析急性心肌梗死患者入院时及治疗后不同时间肌红蛋白和肌钙蛋白的变化情况，并与对照组比较。结果：与对照组相比，研究组急性心肌梗死患者肌红蛋白和肌钙蛋白水平均明显高，差异有统计学意义(P<0.01)。研究组急性心肌梗死患者肌红蛋白水平入院2 h后出现上升趋势，8 h后达到峰值，12 h后出现回落，72 h后降至正常水平。肌钙蛋白水平入院后4 h出现上升趋势，12 h后达到峰值，24 h后出现回落，72 h后降至正常水平。结论：肌红蛋白和肌钙蛋白水平的检测对于急性心肌梗死患者早期诊断以及治疗各具优势，可联合应用。%Objective:To explore the clinical significance of myoglobin combined with troponin in early diagnosis of acute myocardial infarction. Method:From May 2014 to April 2015,85 acute myocardial infarction patients in our hospital were selected as the study group.90 healthy subjects examination in our hospital were selected as the control group.The myoglobin and troponin changes in different time at admission and after treatment in two groups were compared and analyzed,and compared with the control group.Result:Compared with control group,the levels of myoglobin and troponin in the study group were increased significantly,the differences were highly significant statistically(P<0.01).The acute myocardial infarction patients in the study group,the level of myoglobin showed upward trend after 2 h in hospital,reached peak after 8 h,appear to fall after 12 h,reduced to normal after 72 h.The level of troponin shown upward trend after 4 h in hospital,reached peak after 12 h,appear to fall after 24 h,reduced to normal after 72 h.Conclusion:Myoglobin and troponin levels detected have advantages for early diagnosis and treatment of acute myocardial infarction patients.Combined application has more important for clinical reference value.