A model of cardiac troponin T release in patient with acute myocardial infarction

摘要

The analysis of cardiac damage biomarkers is crucial in the diagnosis and prognosis of acute myocardial infarction. The present work proposes a dynamical model for the analysis of the release in the blood of cardiac troponin T (cTnT). The model, tested against patients data, proves to be an effective tool to extrapolate information of interest to the clinician, like peaks and peak-times of the release curve. Furthermore, the model has been proven efficient to quantitatively differentiate patients with effective and non-effective thrombolysis response, which is a key information to guide revascularization.