磷酸肌酸钠联合高压氧治疗一氧化碳中毒迟发性脑病疗效观察

摘要

Objective:To explore the curative effect of creatine phosphate sodium combined with high pressure oxygen in the treatment of chronic encephalopathy of carbon monoxide poisoning(DEACMP).Methods:43 patients with DEACMP were selected. They were randomly divided into the treatment group and the control group.Patients in the control group were given conventional treatment.Patients in the treatment group were given injection creatine phosphate sodium treatment on the basis of the control group.The curative effects of two groups were observed.Results:The cure rate and effective rate of the treatment group were significantly higher than those of the control group,and the differences were statistically significant(P<0.05).Conclusion:The creatine phosphate sodium can improve the cell energy supply of DEACMP patients,protect the brain function,improve the hypoxia tolerance of brain cells,improve the life quality of DEACMP patients.%目的：探讨磷酸肌酸钠联合高压氧治疗一氧化碳中毒迟发性脑病(DEACMP)的疗效。方法：收治DEACMP患者43例，随机分为治疗组和对照组。对照组给予常规治疗，治疗组则在对照组的基础上加注射用磷酸肌酸钠治疗。观察两组患者的疗效。结果：治疗组治愈率及有效率均明显高于对照组，差异有统计学意义(P＜0.05)。结论：磷酸肌酸钠可以改善DEACMP患者的细胞能量供应，保护脑功能，提高脑细胞对缺氧的耐受性，提高DEACMP患者的生活质量。