CenterforAnimalTransgenesisandGermCellResearch,SchoolofVeteriltaryMedicine,DepartmentofAnimalBiology,UniversityofPennsylvania,KennettSquare,Pennsyloania19348;
InstituteofPharmacologyandStateKeyLaboratoryofBiomembraneandMembraneBiotechnology;
InstituteofPharmacologyandStateKeyLaboratoryofBiomembraneandMembraneBiotechnology//DepartmentofBiologyandBiotechnology,TsinghuaUniversity,BeijingChina;
InstituteofPharmacologyandStateKeyLaboratoryofBiomembraneandMembraneBiotechnology//DepartmentofPharmacology,UniversityofMinnesota,Minneapolis,Minnesota55455;