PCL/PVP 共混膜的制备及其性能研究

摘要

利用溶液浇铸法制备了聚ε-己内酯(PCL)/聚乙烯吡咯烷酮(PVP)共混膜,分析了PCL/PVP共混膜的结晶性能、相容性、力学性能、亲水性和生物降解性能.结果表明:PVP的加入对PCL的结晶晶型无影响,但产生了稀释作用,两者可以相容且在共混过程中未发生化学反应；一定含量的PVP有助于增强共混膜的力学性能,PVP的质量分数为20％时,PCL/PVP共混膜力学性能最佳；随着PVP含量的增加,共混膜与水的接触角减小,吸水率逐步增大,PCL的亲水性得到改善；PCL/PVP共混膜在磷酸盐缓冲液中的失重率随PVP含量的增加而增大,且共混膜的失重率逐渐由PCL主导过渡到PVP主导,加入脂肪酶可加速PCL/PVP共混膜的降解.%Poly( e -caprolactone) (PCL)/ polyvinylpyrrolidone (PVP) blend membrane was prepared by solution casting method. The crystallization behavior, compatibility, mechanical properties, hydrophilicity and biodegradability of PCL/PVP blend membrane were analyzed. The results showed that the addition of PVP did not affect the crystal form of PCL, but offered dilution effect; PVP was compatible with PCL and no chemical reaction occurred during the blending process; a specific amount of PVP was helpful to improving the mechanical properties of blend membrane, which was optimized as PVP mass fraction was 20% ; the contact angle between blend membrane and water decreased, the water absorption gradually increased and the hydrophilicity of PCL was improved as PVP content was increased; the weight loss rate of PCL/PVP blend membrane in phosphate buffer was increased with the increase of PVP content and was gradually transformed from PCL-dominated to PVP-dominated, and the addition of lipase accelerated the degradation of PCL/PVP blend membrane.