一个基于主客体作用的超两亲分子自组装体系的构筑及其光调控

摘要

A molecule containing azobenzene and cholesterol moieties (AzoChol)was synthesized,which forms supra-amphiphile with α-cyclodextrin (α-CD)based on host-guest interaction between azo group andα-CD. The supra -amphiphile AzoChol/α -CD self -assembled into vesicles in water,demonstrated by transmission electron microscopy (TEM ),atomic force microscope (AFM ) and confocal laser scanning microscope (CLSM). The azo group shows trans-cis photoisomerization by UV and visible light irradiation. Therefore,the supra-amphiphile AzoChol/α-CD is photo-switchable,leading to the disassembly and re-assembly of vesicles irradiated by UV and visible light alternately. The supra-amphiphilic structure of the new material may display potential applications in field for development of smart materials.%合成了含偶氮苯和胆甾醇基团的分子AzoChol，在主客体作用的驱动下与α－环糊精（α－CD）形成了一个超两亲分子AzoChol／α－CD。利用透射电镜（TEM）、原子力显微镜（AFM）、激光共聚焦电子显微镜（CLSM）等实验手段证明了该超两亲分子在水溶液中自组装形成囊泡结构。偶氮苯基团在光照刺激下可以发生顺反异构的可逆变化，导致超两亲分子的解体和再次形成，进一步引起体系发生囊泡解体与再形成的可逆转变。这种具有光刺激响应的超分子结构的转变在智能材料领域可能具有潜在应用价值。