耐久性运动导致大鼠肾脏组织自由基代谢动态变化的研究

摘要

The activity of Lipid peroxidase contents (LPO), glutathionePeroxidase (GSH-Px) and superoxide dismutase (SOD) in kidney tissue of mice are tested before, immediately after endurance exercise at the end of 2nd, 4th, 6th hours during recovery period. LPO content is increased significantly immediately after endurance exercise in kidney tissue (P<0.01). SOD activity has no apparent increase (P>0.05), and GSH-Px activity decreases significantly (P<0.05). The results indicate that the free radical activity in kidney tissue increases significantly after exercise. As for dynamic changes of LPO, SOD and GSH-Px index based on four time tests, endurance exercise may increase the antioxidative enzyme activity in Kidney tissue, and as a result, it scavenges much more free radical resulting from exercise and enhances the ability for anti-free radical.%测定大鼠在进行耐久性运动前及运动后即刻、2h、4h及6h肾脏组织脂质过氧化水平（LPO）、超氧化物歧化酶（SOD）活性、谷胱甘肽过氧化物酶（GSH-Px）活性和尿总蛋白排出率（TP）变化表明，大鼠肾脏组织在运动结束后即刻LPO和尿TP排出率显著升高（P<0.01，P<0.01），SOD活性升高不显著（P>0.05）和GSH-Px活性显著下降（P<0.05）。大鼠肾脏组织在运动结束后即刻自由基作用明显加强，从其在运动结束后4次测得肾脏组织LPO、SOD、GSH-Px和尿TP排出率指标所形成的动态变化看，耐久性运动可以提高大鼠肾脏组织抗氧化酶活性，从而清除运动时产生的大量自由基，提高大鼠肾脏组织对抗自由基的能力。