基于液质联用技术的蒙药扑勒蒙化学成分分析与鉴定

摘要

To rapidly separate and identify the chemical constituents in Artemisia sphaerocephala Krasch.,the ethanol extracts were investigated by using HPLC-ESI-MS/MS technique.Eleven compounds were separated and identified.Their structures are characterized as caffeic acid,5,7,2’,4’-tetrahydroxy-6,5’-dimethoxyflavone,quercetagetin,4’-hydroxywogonin,quercetaget-in-4’-methyl ether, 5,6,3 ’-trihydroxy-7,4 ’-dimethoxyflavanone, eriodictyol-7-methyl ether, quercetin-7- methyl ether, sakuranetin,isosakuranetin,3,5-dihydroxy-7,4’-dimethoxy-flavanone.%针对蒙药扑勒蒙化学成分的快速分离与鉴定，采用液质联用技术对其乙醇提取物进行了研究，从中分离鉴定了11个化合物，其化学结构分别为咖啡酸、5，7，2’，4’-四羟基-6，5’-二甲氧基黄酮、槲皮万寿菊素、4’-羟基汉黄芩素、槲皮万寿菊素-4’-甲醚、5，6，3’-三羟基-7，4’-二甲氧基黄烷酮、圣草酚-7-甲醚、槲皮素-7-甲醚、樱花素、异樱花素和3，5-二羟基-7，4’-二甲氧基黄烷酮。