探究全肠外营养对早产儿营养、免疫功能及行为发育的影响效果

摘要

目的：探究早产儿给予全肠外营养治疗对其营养、免疫功能及行为发育的影响。方法50例早产儿,随机分成对照组和观察组,每组25例。对照组进行常规治疗,观察组在常规治疗基础上给予全肠外营养,比较两组效果。结果观察组患儿日平均增长体重为(23.2±5.3)g,高于对照组的(8.3±2.9)g,差异具有统计学意义(P<0.05)；观察组球蛋白水平为(23.6±1.9)g,高于对照组的(15.8±1.7)g,差异具有统计学意义(P<0.05)；观察组白蛋白水平为(39.8±4.2)g,高于对照组的(31.2±3.5)g,差异有统计学意义(P<0.05)。观察组各免疫功能指标均优于对照组,差异具有统计学意义(P<0.05)。观察组行为能力得分为(11.2±1.5)分,对照组为(9.6±1.1)分,观察组行为能力得分明显高于对照组(P<0.05)；观察组被动肌张力得分为(7.7±1.2)分,对照组为(5.9±0.8)分,观察组被动肌张力得分明显高于对照组(P<0.05)；观察组主动肌张力得分为(7.9±1.8)分,对照组为(6.2±1.2)分,观察组主动肌张力得分高于对照组(P<0.05)。结论全肠外营养用于早产儿的治疗中,能够增强其营养,促进行为发育,提升免疫功能,值得推广。%Objective To investigate influence by total parenteral nutrition on nutrition, immune function and behavioral development in premature infant. Methods A total of 50 premature infants were randomly divided into control group and observation group, with 25 cases in each group. The control group received conventional therapy, and the observation group received additional total parenteral nutrition to conventional therapy. Effects were compared between the two groups. Results The observation group had higher daily mean ponderal growth as (23.2±5.3) g than (8.3±2.9) g in the control group, and the difference had statistical significance (P<0.05). The observation group had higher globulin as (23.6±1.9) g than (15.8±1.7) g in the control group, and the difference had statistical significance (P<0.05). The observation group had higher albumin as (39.8±4.2) g than (31.2±3.5) g in the control group, and the difference had statistical significance (P<0.05). The observation group had all better immune function indexes than the control group, and the difference had statistical significance (P<0.05). The observation group had active ability score as (11.2±1.5) points, which was (9.6±1.1) points in the control group, and the observation group had obviously higher active ability score than the control group (P<0.05). The observation group had passive muscular tension score as (7.7±1.2) points, which was (5.9±0.8) points in the control group, and the observation group had obviously higher passive muscular tension score than the control group (P<0.05). The observation group had active muscular tension score as (7.9±1.8) points, which was (6.2±1.2) points in the control group, and the observation group had higher active muscular tension score than the control group(P<0.05). Conclusion Implement of total parenteral nutrition in treating premature infant can enhance nutrition, accelerate behavioral development and improve immune function. This method is worth promoting.