参芝消平胶囊质量标准的提高

摘要

Objective: To establish the quality standard for Shenzhi Xiaoping capsules. Methods: The characteristics of Astragali Radix were identified by microscopy. TLC was adopted to identify Astragali Radix, Fructus Aurantii and Glycyrrhiza uralensis. The con-tent of ginsenoside Rb1in Panax ginseng was determined by HPLC. Results: The microscopic characteristics were obvious. The TLC spots were clear with highly specific identification and good separation. The linear range of ginsenoside Rb1was 47. 06-376. 5 μg· ml-1(r=0. 999 9), and the average recovery was 102. 7% with the RSD of 1. 1% (n=6). Conclusion: The method is simple and specific, which can be used for the quality control of Shenzhi Xiaoping capsules.%目的:建立参芝消平胶囊的质量标准.方法:采用显微镜对黄芪进行显微特征鉴别;采用TLC法对参芝消平胶囊中黄芪、枳壳、甘草进行定性鉴别;采用HPLC法测定人参中人参皂苷Rb1的含量.结果:显微特征明显;TLC鉴别黄芪、枳壳、甘草特征斑点清晰,分离度良好;含量测定人参皂苷Rb1在47. 06~376. 5 μg·ml-1范围内线性关系良好(r=0. 999 9),平均回收率为102. 7% ,RSD为1. 1% (n=6).结论:本方法简便易行,专属性强,可用于参芝消平胶囊的质量控制.