目的：分析某医院住院患者抑酸药的应用情况，为临床合理用药提供参考。方法随机抽查该院2012年1月至12月期间住院患者抑酸药使用情况，统计抑酸药消耗数量、金额及科室分布，对用药频度、使用强度、抑酸药使用率、人均费用及适应证等进行统计和分析。结果住院患者抑酸药使用以质子泵抑制剂（PPI）占主导，主要采用静脉给药。内科使用频度占全院的71.75%，涉及消化、呼吸、心内、老年科等；外科占28.25%。住院患者使用率为37.24%，内科以消化、血液肿瘤、呼吸科使用率较高；外科以重症医学室( ICU )、脑外、肝胆等科室为主；人均费用200元以上。结论 PPI在ICU和非ICU患者中使用非常广泛，其使用方式和合理性值得探讨，有待规范。%Objective To analyze the use situation of acid-suppressive drugs in the inpatients so as to provide reference for the clini-cal rational use of drugs. Methods The random check on the use situation of acid-suppressive drugs in the inpatients was monthly conducted from January to June 2012, the consumption quantity, sales amount, department distribution, DDDs, use intensity, utilization rate of acid-suppressive medications, per capita costs and indications were performed the statistics analysis. Resuts In the acid-suppressive drugs use, the proton pump inhibitors ( PPI ) were predominant and mainly adopted the intravenous administration. The percentage of use frequency in internal medicine was 71. 75%, involving the digestion, respiration, cardiology, geriatrics, etc. Surgery was 28. 25%. The inpa-tient utilization rate was 37. 24%. In internal medicine, the digestive, hematological tumor and respiratory departments had the higher use rate of acid-suppressive drugs;surgery was dominated by critical care medicine, brain surgery and hepatobiliary departments. Per capita costs was over 200 Yuan. Conclusion PPI are very widely used in ICU and non-ICU patients, its use mode and rationality deserve to explore and need to be standardized.
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