胸腺肽α1免疫调节对高龄老年肺部感染的应用价值分析

摘要

Objective To observe the application value of thymosin α1 immunoregulation in senile pulmonary infection. Methods 74 cases of senile pulmonary infection treated in our hospital were divided into the observation group ( 37 cases ) and the control group ( 37 cases ) . The control group was treated by the routine therapy of pulmonary infection, while on this basis the observation group was performed the thymosin α1 immunoregulation therapy. The clinical treatment effects were assessed in the two groups. The immunological indexes and inflammation reaction indexes were detected before and after therapy. Results The total effective rate of the clinical thera-py in the observation group was 91. 89%, which was higher than 78. 38% in the control group, the difference between the two groups was statistically significant ( P 0. 05 ) . At the same time, the IL-6, IL-8 and TNF-α levels after treatment in the observation group were lower than those in the control group ( P 0.05）。治疗后观察组患者的白细胞介素－6( IL－6)、IL－8、肿瘤坏死因子－α( TNF－α)水平均低于对照组（ P<0.05）。结论在高龄老年肺部感染临床治疗中，辅助应用胸腺肽α1免疫调节治疗，能有效提高患者的免疫功能，提高机体炎症因子的改善效果，促进提高临床疗效。