六水合三氯化铁中亚铁的检测方法探讨

摘要

目的 建立测定六水合三氯化铁中亚铁含量的分光光度法.方法 通过比较欧洲药典、美国药典和中国化工行业《化学试剂六水合三氯化铁(三氯化铁)》(HG/T3474-2014)等资料中关于六水合三氯化铁中亚铁的检测方法,发现后2个方法不易操作.以欧洲药典为基础,拟订了用H3PO4掩蔽Fe3+、用分光光度法检测Fe2+的方法,并用样品对方法进行了验证.结果与结论 所建立的分光光度法容易操作、重复性好.%Objective To establish a spectrophotometric method for the determination of ferrous iron in ferric chloride hexahydrate. Methods The detection methods on ferrous iron in ferric chloride hexahydrate among European Pharmacopoeia,United States Pharma-copoeia and Chemical Reagent Ferric Chloride Hexahydrate(HG/T3474-2014)of China's Chemical Industry were compared. The last two methods were not easy to operation. On the basis of the European Pharmacopoeia,a method was proposed that after Fe3+ were screened with H3PO4,Fe2+ was measured by spectrophotometry,and the method was verified by experiments. Results and Conclusion The spectrophotometry method is easy to operate and has good reproducibility.