Objective To investigate the application of osteoporosis drugs in outpatient of our hospital, in order to provide reference for clinical medication. Methods Totally 2000 prescriptions of osteoporosis in our hospital were retrospective analyzed. The application of drug use was statistically analyzed , the sum of drug use and the frequency of drug use ( DDDs ) was analyzed , and the clinical application of various drugs was evaluated by drug utilization analysis method. Results Calcitriol, Vitamin D calcium, alendronate sodium, calcium carbonate D3 were the most widely used drugs, accounted for 75. 00％, 7. 50％, 5. 00％, 5. 00％, respectively. Calcitriol accounted for the first DDDs in outpatient prescriptions, the ratio of the order of sum of drugs use and DDDs was 1 : 0, and the synchronism was good. Conclusion The prevention and treatment of osteoporosis is a long process, and active vitamin D and its metabolites, bisphosphonates and calcium preparations are commonly used drugs in our hospital, DDD, DDDs and other drug economic data have higher practical significance for clinical treatment.%目的 探讨医院门诊骨质疏松症(OP)药物应用状况,为临床用药提供参考.方法 回顾性分析医院门诊OP处方2000份,统计用药情况,采用药物利用分析法,分析用药金额、用药频度(DDDs),评价各类药物在临床实际应用情况.结果 骨化三醇、维D钙、阿仑膦酸钠及碳酸钙D3用药最多,分别占75.00％,7.50％,5.00％,5.00％;骨化三醇DDDs占首位,且用药金额排序与DDDs排序比值为1.0,同步性好.结论 防治OP是一个漫长的过程,活性维生素D及代谢产物、双膦酸盐类、钙制剂是医院门诊常用治疗药物,DDD和DDDs等药物经济学数据对临床治疗具有较高的实际指导意义.
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