To solve the increasingly serious problem of ＂many wells, but low productivity＂ in China, the hydraulic jetting fracturing technology with coiled tubing, as a new measure for effectively improving the production rate of individual well and enhancing oil and gas recovery, merits much attention nowa- days. On the basis of study of the hydraulic jetting fracturing mechanism with coiled tubing and numerical simulation of pressure distribution inside the pores, the mechanism of pressure rise inside the pores caused by the pressure boost action within the jetting pore and the hydraulic isolation action is examined, and the influence of main parameters on the pressure distribution inside the pores is analyzed. 3 kinds of operating methods of hydraulic jetting fracturing with coiled tubing are raised with the tubular diameter of coiled tub- ing as an important feature parameter. According to the experimental study, the fracturing mechanism and computational resuks of numerical simulation are both examined. It is considered that under the same pres- sure drop of jet nozzle, the pressure inside the pores increases with the confining pressure nearly at a line- ar state. When the vertical depth of the borehole is rather big and the rupture pressure of the formation is higher, it is recommended to use higher pressure drop of jet nozzle for achieving better pressure boost and hydraulic isolation effect. For the hydraulic jetting fracturing with coiled tubing, the coiled tubing with tu- bular diameter not less than 50. 8 mm （2 in. ） is usually used.
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