参松养心胶囊对冠状动脉粥样硬化性心脏病患者QT离散度的影响

摘要

Objective To observe the effect of Shensongyangxin capsule on QT dispersion (QTd) of patients with coronary heart disease (CHD). Methods Ninety-two cases of CHD were randomized into the treatment group (47 cases) with Shensongyangxin capsule and control group (45 cases), then respectively observing. Changes of QTd, QTcd before and after treatment. Results The results showed QTd and QTcd reduced after treatment in the two groups, but the Shensangyangxin capsule group reduced more significantly (P < 0.05).Conclusion Shensongyangxin Capsule can reduce QTd effectively and prevent ventridea rrhythmia.%目的 观察参松养心胶囊对冠状动脉粥样硬化性心脏病(冠心病)患者QT离散度(QTd)的影响.方法 92例冠心病患者用随机数字表法分为治疗组47例和对照组45例,2组均给予相同的常规治疗,治疗组在此基础上加用参松养心胶囊1.6 g/次,3次/d口服.观察2组患者治疗前后QTd及校正后QTd(QTcd)的变化.结果 与治疗前相比,2组患者治疗后QTd、QTcd均显著缩小[治疗组QTd、QTcd分别为(38.2±19.1)ms和(32.2±16.1)ms,对照组分别为(48.6±18.9)ms和(42.3±17.9)ms],与本组治疗前相比,差异有统计学意义(P<0.01);治疗组缩小幅度更明显,差异有统计学意义(P<0.05).结论 参松养心胶囊可有效缩小QTd和QTcd,起到防治室性心律失常的作用.