肺功能改善的临床探讨

摘要

Objective To study the effects and mechanisms of respiratory exercise on improving pulmonary function of chronic obstructive pulmonary disease (COPD) patients.Methods Sixty patients with COPD were randomly allocated into control group and intervention group.Patients in two groups received routine medicine therapy and scheduled healthy knowledge education.Patients in the intervention group was asked to do respiratory exercise additionally.6-minute walk distance,serum leukotriene and fractional exhaled nitric oxide (FENO) were measured.Results Compared with control group,the ability of 6-minute walk distance in the intervention group was improved significantly,and serum leukotriene was significantly decreased ( P ＜ 0.01 ),as well as FENO decreased (P ＜0.01 ).Conclusion Respiratory exercise,particularly general breathing exercise,can improve pulmonary function and quality of life of COPD patients.%目的 探讨呼吸康复训练和常规治疗对改善慢性阻塞性肺疾病(COPD)患者肺功能的效果比较.方法 选2010年6月至2011年5月我院60例COPD患者,按随机数字表法将其分为对照组和研究组,各30例.对照组予常规内科治疗并对其进行健康知识教育及一般康复训练,研究组在对照组治疗方案基础上,增加呼吸操训练.对比2组干预前后肺功能、6 min步行距离、血清白三烯、呼出气一氧化氮(FENO)的变化.结果 研究组肺功能比对照组明显改善,组间差异有统计学意义(P＜0.01);6 min步行距离明显改善,组间差异有统计学意义(P＜0.01);血清白三烯水平明显下降,组间差异有统计学意义(P＜0.01);FENO含量明显下降,组间差异有统计学意义(P＜0.01).结论 呼吸康复训练,尤其全身性呼吸操能明显改善COPD患者肺功能,提高患者的活动耐力,改善生活质量.