Objective To analyze the value of the SYNTAX score in therapeutic effect and prognosis prediction of percutaneous coronary intervention (PCI) in patients with coronary atherosclerotic heart disease (CHD).Methods A total of 130 CHD patients admitted in Qinghai Provincial Cardio-Cerebrovascular Disease Hospital from February 2015 to August 2016 were divided into 3 groups according to the SYNTAX score after PCI:group A (SYNTAX score > 32,n =42),group B (SYNTAX score 23-32,n =43) and group C (SYNTAX score <23,n =45).Clinical efficiency and prognosis were analyzed among groups.Results There were no significant differences of left ventricular ejection fraction,left ventricular end-diastolic diameter and cardiac output among 3 groups before treatment (P > 0.05).Twelve months after treatment,left ventricular ejection fraction,left ventricular end-diastolic diameter and cardiac output in group C were significantly higher than those in group A and B[(68.4±3.4)% vs (63.8 ±3.5)%,(64.3 ±2.7)%;(62.6±1.2)mmvs (46.1 ±3.4),(48.2±3.3)mm;(5.5 ± 0.4) L vs (4.6 ± 0.3),(5.0 ± 0.9) L] (P < 0.05).During 12 months after treatment,incidence of cardio-cerebrovascular adverse events in group C was significantly lower than that in group A and B[4.4% (2/45) vs 28.6% (12/42),20.9 % (9/43)] (P < 0.05);hospitalization times in group C were significantly less than those in group A and B[(0.52 ±0.12) times/year vs (1.81 ±0.22),(1.21 ±0.12) times/year];length of hospitalization time in group C was significantly shorter than that in group A and B [(7.0 ± 1.0) d vs (9.8 ± 1.2),(8.4 ±1.3) d] (P < 0.05).Conclusion Low SYNTAX score after PCI suggests optimistic therapeutic response and prognosis in CHD patients.%目的 探讨冠状动脉粥样硬化性心脏病(冠心病)患者经皮冠状动脉介入(PCI)治疗后效果评价、预后预测中应用SYNTAX积分的效果.方法 选取2015年2月至2016年8月在青海省心脑血管病专科医院接受PCI治疗的冠心病患者130例,依据术后SYNTAX积分将患者分为3组,A组(SYNTAX积分>32分)42例,B组(SYNTAX积分23 ~ 32分)43例,C组(SYNTAX积分<23分)45例.比较3组患者疗效及预后.结果 治疗前,3组患者左心室射血分数、左心室舒张末期内径、心排血量比较,差异均无统计学意义(均P>0.05);治疗后12个月,3组左心室射血分数、左心室舒张末期内径、心排血量均较治疗前改善,3组间比较,C组改善较A、B组明显[(68.4±3.4)%比(63.8±3.5)%、(64.3±2.7)%;(62.6±1.2)mm比(46.1±3.4)、(48.2 ±3.3)mm;(5.5 ±0.4)L比(4.6±0.3)、(5.0±0.9)L],差异均有统计学意义(均P <0.05).PCI术后随访12个月,C组心脑血管不良事件发生率明显低于A、B组[4.4%(2/45)比28.6% (12/42)、20.9% (9/43)],差异均有统计学意义(均P<0.05).随访期间,C组患者住院次数明显少于A、B组[(0.52±0.12)次/年比(1.81 ±0.22)、(1.21±0.12)次/年],住院时间明显短于A、B组[(7.0±1.0)d比(9.8±1.2)、(8.4±1.3)d],差异均有统计学意义(均P<0.05).结论 对于接受PCI治疗的冠心病患者,术后SYNTAX积分越低表示治疗效果和预后越好.因此,SYNTAX积分可作为此类患者效果评价及预后预测的一个依据.
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