首页> 中文期刊> 《中国医药科学》 >单磷酸阿糖腺苷联合泛昔洛韦、薄芝糖肽治疗带状疱疹92例疗效观察

单磷酸阿糖腺苷联合泛昔洛韦、薄芝糖肽治疗带状疱疹92例疗效观察

         

摘要

目的:探讨单磷酸阿糖腺苷联合薄芝糖肽治疗带状疱疹的临床治疗效果及应用价值。方法选择我院治疗的带状疱疹患者92例,随机分为观察组和对照组,对照组采用泛昔洛韦联合薄芝糖肽、维生素B1、维生素B12治疗,观察组在对照组治疗的基础上给予单磷酸阿糖腺苷进行治疗,观察两组的临床治疗效果。结果观察组总有效率高于对照组,经统计学分析比较,差异有统计学意义(P<0.05)。观察组患者水疱干涸结痂、疼痛缓解、疼痛消失时间、后遗神经痛发生率均优于对照组,经统计学分析比较,差异有统计学意义(P<0.05)。结论采用单磷酸阿糖腺苷联合泛昔洛韦、薄芝糖肽治疗带状疱疹起效快,疗效显著,降低后遗神经痛发生率,值得在临床大力推广使用。%Objective To discuss the clinical treatment effect and application value of vidarabine monophosphate combined with bozhi glycopeptide in the treatment of patients with herpes zoster. Methods Ninety-two patients with herpes zoster who received treatment in our hospital were chose and randomly divided into the observation group and the control group. The patients in the control group were treated with famciclovir combined with Bozhi glycopeptide and vitamin B1, vitamin B12, while the patients in the observation group were treated with vidarabine monophosphate on the basis of the control group. The clinical therapeutic effect of two groups was observed. Results The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P<0.05). The blister drying and scabbing, pain relieving, pain disappearing time and incidence of neuralgia of patients in the observation group were better than those in the control group, the differences were statistically significant(P<0.05). Conclusion Using vidarabine monophosphate combined with famciclovir and bozhi glycopeptide in the treatment of patients with herpes zoster has rapid onset, significant curative effect, and reduces the incidence of neuralgia, and it is worthy of popularizing in clinical use.

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