天智颗粒治疗急性脑梗死后认知功能障碍的疗效观察

摘要

目的 探讨天智颗粒对急性脑梗死后认知功能障碍的临床疗效.方法 将入选的120例患者随机分成天智颗粒组(治疗组,60例),基础治疗组(对照组,60例).两组均3个月为1个疗程.应用中文版蒙特利尔认知评估量表(Montreal cognitive assessment scale,MoCA)对治疗前后进行认知功能评定.结果 两组治疗后各条目及总分均较治疗前有明显提高,其中天智颗粒组治疗前后除延迟记忆外,其他各条目及总分比较有统计学意义(P＜0.05)；对照组治疗前后有延迟回忆、定向两个条目比较无统计学意义(P＞0.05)；两组治疗后得分比较,除延迟记忆、抽象两条目外,余条目及总分天智颗粒组均高于对照组且有统计学意义(P＜0.05).结论 天智颗粒有助于改善急性脑梗死后的认知功能障碍.%Objective To explore the effect of Tianzhi Granule in the treatment of cognition disorder after acute cerebral infarction (ACI).Methods 120 cases with cognition disorder after acute cerebral infarction (ACI) were randomly divided into Tianzhi Granule group (60 cases) and control group (60 cases).3 months were a treatment course for two groups.The cognitive of two groups were assessed by the Chinese version of montreal cognitive assessment scale (moCA) before and after treatment.Results Compared with before treatment,the scores of MoCA in the two groups after treatment were higher,and there were significant difference in the scores of MoCA (excepting the item of delayed recall)of Tianzhi Granule group (P ＜ 0.05); there were not significant difference in the scores of MoCA (the items of delayed recall and direction) of control group (P ＞ 0.05); there were significant difference in the scores of MoCA (excepting the items of delayed recall and abstract) after treatment between the two groups (P ＜ 0.05).Conclusion Tianzhi Granule can improve the cognition disorder after ACI.