超声光散射断层成像技术在早期乳腺肿块定性诊断中的应用研究

摘要

Objective:To discuss the applied value of the ultrasonic light scattering imaging DOT technology in the diagnosis of early breast lumps. Methods: The data of 114 patients that were experted ultrasound imaging of light scattering and were with clear pathological diagnosis results were analyzed retrospectively in our department in three years. Diagnostic indicators (SDI), the mass of the total amount of hemoglobin (HBT), oxygen saturation (SO2), mass direction (Orien) form factor (Forml) and the posterior echo (Pecho) were recorded, and the diagnostic sensitivity, specificity, positive predictive value, negative predictive value, false negative rate and false positive rate were analyzed. The results were proceed and analyzed through SPSS 17.0. Results:There were significant differences in the SDI, HBT, Orien, Forml(t=-4.122,t=-2.275,t=-2.206,t=-2.927,P<0.05)The diagnostic sensitivity was 95.7%, specificity was 95.5%, positive predictive value was 93.8%, negative predictive value was 97.0%,false negative rate was 4.3%and false positive rate was 4.5%. Conclusion: Light scattering of ultrasound imaging use SDI, HBT, Orien, the Forml four quantitative indicators, qualitative evaluation can reach the masses, has a higher value in the differential diagnosis.%目的：讨论超声光散射断层成像(DOT)技术在早期乳腺肿块定性诊断中的应用价值。方法：对梅河口市中心医院超声科3年间行超声光散射成像检查并有明确病理诊断结果的114例患者资料进行回顾性总结分析，记录综合诊断指标(SDI)，肿块的血红蛋白总量(HBT)，血氧饱和度(SO2)，肿块方向(Orien)，形态因子(Forml)以及后方回声(pEcho)，并分析诊断灵敏度、特异度、阳性预测值、阴性预测值、假阴性率和假阳性率，并采用SPSS17.0进行数据处理分析。结果：良、恶性肿块在SDI、HBT、Orien、Forml上具有显著性差异(t=-4.122，t=-2.275，t=-2.206，t=-2.927，P＜0.05)诊断灵敏度为95.7%，特异度为95.5%，阳性预测值为93.8%，阴性预测值为97.0%，假阴性率为4.3%，假阳性率为4.5%。结论：超声光散射成像利用SDI、HBT、Orien及Forml4个量化指标，能够达到对肿块的定性评价，具有较高的鉴别诊断价值。