功能磁共振在神经外科手术计划中的应用

摘要

With the development of functional MRI (fMRI), it has been widely applied in neurosurgery to improve the surgical outcomes. This article reviewed the usage of task-based fMRI, diffusion tensor imaging (DTI) and resting-state fMRI (rs-fMRI) in neurosurgery. At present, task-based fMRI and DTI tractography has been used in the preoperative planning of the surgical corridor, quantifying the spatial relationship between lesion and functional brain areas, and evaluating surgical risks. Research about rs-fMRI elucidates its potential in the location of neurological function areas, neurocognitive areas and epileptogenic focus. FMRI will play more important role in improving the neurosurgical outcomes in the future.%随着功能磁共振(functional MRI,fMRI)技术的发展,fMRI技术已经在神经外科得到了越来越广泛的应用,以保护脑功能进而提高手术预后.本综述对任务态fMRI、弥散张量成像(Diffusion Tensor Imaging,DTI)及静息态fMRI(rs-fMRI)技术在神经外科手术计划中的应用进行了探讨.目前任务态fMRI与DTI纤维束追踪技术已经广泛应用于神经外科手术术前计划中,用以评估病灶与功能区的空间关系,具有较高的稳定性及可靠性.rs-fMRI相关研究也表明其在对于神经功能区、神经认知功能区、致痫灶的判断及定位方面的临床应用潜力.随着磁共振技术的不断完善,fMRI将进一步提高神经外科手术预后.